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American Society of Microbiology ABMM Sample Questions (Q183-Q188):
NEW QUESTION # 183
A research laboratory is investigating the mechanism of action of a novel antiviral compound that inhibits the replication of a specific RNA virus. They find that the compound binds directly to the viral RNA-dependent RNA polymerase, preventing its elongation activity. This mechanism is most similar to that of:
- A. Ribavirin
- B. Acyclovir
- C. Interferon-beta
- D. Oseltamivir
Answer: A
NEW QUESTION # 184
A clinical microbiology laboratory is preparing to validate a new molecular assay for the detection of methicillin-resistant Staphylococcus aureus (MRSA). To assess the positive predictive value (PPV) of the assay, they need to know:
- A. The number of true negative results divided by the total number of true negative and false positive results.
- B. The number of true positive results divided by the total number of positive test results.
- C. The number of true negative results divided by the total number of negative test results.
- D. The number of true positive results divided by the total number of true positive and false negative results.
Answer: B
NEW QUESTION # 185
The human virome, the collection of viruses that reside in and on the human body, is increasinglyrecognized for its role in health and disease. Which of the following statements regarding the human virome is MOST accurate?
- A. The human virome is largely independent of the host's immune status.
- B. The human virome is primarily composed of pathogenic viruses that cause acute infections.
- C. The composition of the human virome is relatively stable over time and is not influenced by environmental factors.
- D. Bacteriophages, viruses that infect bacteria, are a significant component of the human gut virome.
Answer: D
NEW QUESTION # 186
A clinical microbiology laboratory is implementing a new multiplex nucleic acid amplification test (NAAT) for the detection of respiratory viral pathogens. To ensure the quantitative accuracy of the assay, it is essential to include:
- A. Internal controls to monitor for PCR inhibition.
- B. Only positive and negative controls.
- C. Calibration standards with known concentrations of target nucleic acids.
- D. External quality assessment samples.
Answer: C
NEW QUESTION # 187
The direct fluorescent antibody (DFA) test is commonly used for the rapid detection of which respiratory pathogen directly from nasopharyngeal specimens?
- A. Influenza virus
- B. Bordetella pertussis
- C. Legionella pneumophila (serogroup 1 in sputum)
- D. Mycoplasma pneumoniae
Answer: B
NEW QUESTION # 188
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